UMKC Innovation Center partners with the university and the community to spark and sustain entrepreneurial efforts within our region and across the country.

KCSourceLink connects KC entrepreneurs to the right resource at the right time.

MOSourceLink connects Missouri entrepreneurs to the right resource at the right time.

Whiteboard2Boardroom connects entrepreneurs and businesses to technologies available for licensing.

Digital Sandbox KC provides early-stage proof-of-concept support for digital products.

Missouri Small Business & Technology Development Center provides technical assistance to startup and existing businesses.

ScaleUP! Kansas City helps businesses with revenues around $200K scale toward their first $1 million.

Missouri Procurement Technical Assistance Centers helps local businesses obtain government contracts.

KCInvestED helps investors learn more about investing in KC startups.

SourceLink® helps communities nationwide build vibrant and vital entrepreneurial ecosystems.
UMKC Innovation Center

Missouri Equity Funds

Small Business Investment Companies (SBIC)

Small Business Investment Companies (SBIC) are venture capital firms that receive loans from the Small Business Administration to make equity investments in small businesses. Venture capital firms do not have to be regulated, but must submit to regulation if they want to be an SBIC.

Venture Capital

Venture capital firms tend to be specialized in specific industries and tend to only invest in those industries. VCs want to invest money in companies that can realistically expect high rates of growth, 20% or more, for at least several years. They take partial ownership in the business, and therefore expect to have a say in how the business is operated.

The following are located in Missouri:


3x5 Partners

3x5 Partners is a growth-oriented life science and natural resources venture capital firm. We provide our investors with wealth-creating private equity opportunities.

Advantage Capital Partners

Advantage Capital Partners strives to invest in small businesses and grow local economies. Through a combination of public-private partnerships, Advantage Capital provides access to flexible capital to facilitate growth for businesses.

Alumni Ventures Group

Alumni Ventures Group (AVG) is a different type of venture capital firm. Designed from scratch to meet the needs of the individual accredited investor, AVG provides smart, simple venture portfolios with community.

Ameren Accelerator - UMSL Accelerate

The Ameren Accelerator is an innovative partnership with the University of Missouri System, UMSL Accelerate and Capital Innovators designed to invest, mentor, and accelerate the growth of next-generation energy technologies.

Arsenal Capital Management

Our goal is to provide our investors with a superior investment return by identifying early capital opportunities within a fund structure that is transparent, focused and cost conscious. We are St. Louisians. We take pride in our region and strive to make it a better place to live and work. While we invest where the opportunities are best, we want to help local entrepreneurs build successful companies.

Ascension Health Ventures

Ascension Ventures is a strategic healthcare venture fund with more than $800 million in capital under management. Our limited partners are some of the most respected, values-driven nonprofit healthcare systems in the US.

Atlas Venture

We build breakthrough biotech companies with remarkable life science entrepreneurs.

Bush O'Donnell Capital

Bush O'Donnell Investment Advisors was founded in 1986 and is registered under the Investment Advisors Act of 1940. The firm offers two core products – a Low-Volatility Equity strategy and a Master Limited Partnership strategy.

C3 Capital

C3 Capital is a fund management company based in Kansas City, though the fund’s investment criteria requires existing profitability.

Capital for Business, Inc.

Capital for business is a national private investment firm focused on providing capital to middle-market businesses with proven management teams and a high potential for growth.

Capital Innovators

Capital Innovators provides innovation consulting, entrepreneurial-based programs, and acts as a liaison between corporations and startups. It manages venture funds focused on technology, consumer products, and energy technology and sources the most cutting-edge startups from around the globe for investment and assists in scaling its companies to success. Capital Innovators has also created a world-class Accelerator program that has been ranked as one of the top Accelerators for the last 5 years. Capital Innovators has invested in over 120 companies, which have gone on to raise over $330MM in follow-on funding and have created over 1,100 jobs.

Cultivation Capital

Cultivation capital is a venture capital firm investing in technology, life science and agriculture companies

Dundee Venture Capital

We are generalist investors, preferring high-growth, high-margin tech startups. Our portfolio is a mix of vertical and horizontal enterprise software, consumer brands, and marketplaces.


The efactory is an entrepreneurship center designed to assist startup and growth in new small businesses and continuing education and training in mature organizations.

Evergy Ventures

At Evergy Ventures, our door is always open to innovative and progressive companies within the energy value chain. Our strongest partnerships come from growth equity investments in revenue-generating businesses that are primed for expansion and could benefit from a well-capitalized strategic partner with deep industry knowledge.

Firebrand Ventures

Firebrand Ventures is a new kind of Midwest venture fund. We combine a strong brand, vast network, and deep experience with startup hustle to invest in exceptional early stage software startups.

Five Elms Capital

Five Elms is a growth equity firm exclusively focused on B2B software companies.

Flyover Capital

The mission of Flyover Capital is to assist in creating the next generation of technology success stories in the region.


We help entrepreneurs at all stages of their businesses from startup to succession in mid-Missouri (from Glasgow to Hannibal and from Brookfield to Louisiana).

InvestMidwest Venture Capital Forum

InvestMidwest provides access to capital for emerging, privately held companies to promote entrepreneurship, business growth and expansion in the Midwest, with a focus on technology and life sciences.

iSelect Fund

iSelect is an early stage venture firm which invests in companies that are addressing critical global issues, in large markets, and with financially attractive business models.

KCRise Fund

KCRise Fund is a Kansas City-based venture capital firm which invests in Seed and Series A stage technology companies located in the western half of Missouri and state of Kansas.

Lake of the Ozarks Council of Local Governments

Serving Camden, Laclede, Miller and Morgan counties, working together to help provide the necessary resources to help build strong communities within our region.

Lewis & Clark AgriFood

As a late-stage, growth equity-focused fund, we arrive in the sweet spot between seed/early-stage and the buyout phase, minimizing risk and maximizing value. We work with exceptional entrepreneurs to help scale their business with capital and resources.

Lewis & Clark Ventures

Lewis & Clark Ventures is a St. Louis-based multi-sector venture capital firm.


M25 is an early-stage venture firm based in Chicago, investing solely in companies headquartered in the Midwest.

Mercury Fund

Mercury Fund is an early-stage venture capital firm. With over $300 million under management, Mercury focuses on entrepreneurs and technology innovation originating in the U.S. Midcontinent.

Missouri Innovation Center

Missouri Innovation Center supports the creation of new, high-growth ventures, particularly those with a technology component. This is accomplished by leveraging research and innovation by and with the University of Missouri for the benefit of the region and the State.

Missouri S&T Office of Technology Transfer and Economic Development (TTED)

The Missouri S&T Office of Technology Transfer and Economic Development (TTED) provides support to S&T faculty, students and researchers to provide IP protection, identify licensees and commercialize university inventions, assisting them to convert their innovative ideas into products, technologies, and services that can benefit society.

Missouri SBDC at Missouri University of Science and Technology

The Missouri SBDC offers personalized and extensive services from knowledgeable and helpful professionals focused on your business success.

New Enterprise Associates

As one of the world’s largest and most active venture capital firms, NEA has developed deep domain expertise and insight into our industries of focus. We channel that knowledge into every technology and healthcare investment we make -- at any stage, in any location, around the globe.

Open Prairie Ventures

Open Prairie is a Midwest-based, private equity fund manager providing fund deployment, advisory and strategic planning services.

OpenAir Equity Partners

OPENAIR Equity Partners is a private equity and venture capital firm specializing in early venture, mid venture, late venture and later stage investments.

Pelion Venture Partners

Pelion is an early stage venture capital firm bent on exceeding the expectations of unapologetic entrepreneurs who shoot for the moon. A pursuit made possible by decades of experience, unwavering know-how and (most importantly) gritty, over-the-top determination.

Prelude Ventures

Prelude Ventures is a venture capital firm partnering with entrepreneurs to address climate change.

Prolog Ventures

Prolog provides venture capital for high-growth, revenue-stage companies focused on consumer health and wellness products

RiverVest Venture Partners

RiverVest Venture Partners is a venture capital firm focused on identifying and shaping early stage life science companies to create significant shareholder value. With hands-on, high-level expertise and financial resources, RiverVest supports entrepreneurs by helping them achieve near-term objectives that position their companies for exit. For more information, please visit

Royal Street Ventures

Royal Street Ventures is a Utah-based venture capital firm that has expanded into the Kansas City region.

S2G Ventures

S2G Ventures (Seed 2 Growth) is a multi-stage food and agriculture venture fund investing in entrepreneurs whose products and services meet the shifting demands for healthy and sustainable food.

Sage Capital LLC

Sage Capital is a private equity firm providing long-term capital and expertise for small and middle market businesses in North America. The firm aims to invest in excellent companies and partner with management teams or existing owners. We make both control and minority investments, and we provide capital for growth, acquisitions and recapitalizations alike.

Serra Ventures

Serra Ventures is an early stage venture capital firm investing in technology companies in emerging Midwest technology centers and selected West Coast markets that are underserved. Sectors we focus on include information technology, devices/instrumentation and agricultural technologies.

TechAccel, LLC

TechAccel is a venture development and technology organization that invests across the agriculture, animal health, and food science industries. They work with startups, universities, and corporate partners to fund and advance new discoveries to market.

TGP Investments

TGP Capital Partners is a Kansas City based private equity investment fund formed to make middle-market investments in well-managed, profitable, and growing companies.

The LearningForce

The LearningForce offers a diverse schedule of noncredit continuing education courses for personal enrichment, professional development and workforce training solutions for business, industry and the individual.

The Yield Lab

The Yield Lab is focused on bridging the gap between innovation and fruition of new AgTech by supporting early stage companies. We provide support for within the solid framework of organizations and businesses from the St. Louis area.

Thompson Street Capital Partners

Thompson Street Capital Partners is a St. Louis-based private equity firm focused on investing in founder-led middle market businesses. We have acquired more than 100 companies in the business services, healthcare services and engineered products sectors and have managed more than $1.5 billion in equity across our four funds.

Tradebot Ventures, Inc.

We seek opportunities strategically aligned with our current business and investments.

Triathlon Medical Ventures

Triathlon Medical Ventures is a Midwest-based venture capital firm that invests exclusively in the life sciences. We provide equity capital to early and expansion stage companies with proprietary biomedical technology platforms or products addressing significant human healthcare needs.

University of Missouri–St. Louis - Technology Commercialization & Economic Development

The UMSL Technology Transfer Office helps faculty, staff and students commercialize their research discoveries and creative works through licensing to established companies or new ventures and guiding UMSL entrepreneurs in creating new ventures.

Visionary Private Equity Group

Visionary Private Equity Group (VPEG) invests in early stage, high growth companies that have strong management teams and the potential for significant upside. invests venture and growth capital in founders and management teams with innovative, trans-formative, and game-changing ideas and companies.

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