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Business Incubators

Business incubators provide opportunities to share resources and learn from other businesses.  The list below includes the many business incubators available in Missouri. Also check out technology incubators and wet labs.  

America's Central Port District

America's Central Port District, an economic development corporation, owns and operates southwestern Illinois' only small business incubator: The River's Edge Enterprise Center.

Black Economic Union of Greater Kansas City

BEU is a not-for-profit Community Development Corporation located in the historic Lincoln building at 18th and Vine Kansas City MO. BEU, originated by Jim Brown and Curtis McClinton, helped to pioneer the Community Development movement. BEU is one of the oldest economic development corporation's in the country.

Bloch Venture Hub

3 Levels with 3 purposes - an ideation lab to help entrepreneurs refine, and plan startups; an incubator to launch and aid new ventures with mentoring, education, and other critical resources; and an accelerator to scale and grow young businesses.

Capital Innovators

Capital Innovators is the innovation engine for startups, corporations, and universities. Through our nationally recognized seed program, Capital Innovators has been ranked as a top 10 accelerator for the last four consecutive years.

Center for Emerging Technologies

The Center for Emerging Technologies (CET) provides specialized facilities and business, technology and financing services to early-stage medical (diagnostics, therapies, instrument and devices) and other advanced technology companies.

Chesterfield Department of Planning and Development Services

The Department of Planning and Development Services at the City of Chesterfield is a resource for local entrepreneurs to help grow and expand their businesses.

Economic Development Center (EDC) - St. Charles County

To serve businesses of all sizes, the EDC offers business financing programs, business counseling, tenant space at its nationally-recognized incubator facility, monthly business training seminars and recruitment/retention services.

Economic Development Corporation (EDC) - Kansas City, MO

The Economic Development Corporation (EDC) is a not-for-profit organization with a staff of apx. 30 people that is the City of KCMO's primary development organization & provides assistance to new and expanding businesses already located in Kansas City, Missouri, or those considering a Kansas City location. In addition, the EDC administers the City's TIF program, LCRA, and Enhanced Enterprise/Zone Works program.


The efactory is an entrepreneurship center designed to assist startup and growth in new small businesses and continuing education and training in mature organizations.

Ennovation Center

The Ennovation Center business incubator provides the location and business development services for companies focused in Culinary and Business & Technology.

Helix Center Biotech Incubator

Helix Center Biotech Incubator located near the Danforth Plant Science Center offers 33,000-square-feet of office incubator space, wet and dry labs for early-stage plant and life sciences and bio technology companies.

Hispanic Economic Development Corporation

The Hispanic Economic Development Corporation (HEDC) is dedicated to improving the lives of Latinos within the greater Kansas City. HEDC achieves this through business development and economic and community wealth creation initiatives.

Innovation Stockyard

The Innovation Stockyard operates the Kit Bond Science and Technology Incubator on the campus of Missouri Western State University with a focus on economic and workforce development, and animal health and nutrition.

ITE: Innovative Technology Enterprises at UMSL

ITE at UMSL is a university incubator designed for community as well as university technologies. With office and laboratory space, ITE offers the ideal environment for chemistry, life science, nanotechnology and IT companies.

Joplin Area Chamber of Commerce Foundation

Short Description The Joplin Area Chamber of Commerce Foundation owns and operates the Joseph Newman Innovation Center in Joplin, MO. Our 11,000 square foot building holds several office suites in a beautifully restored building in our downtown district. In partnership with the Joplin Area Chamber of Commerce, our facility is uniquely positioned to offer extensive small business development services through our network with successful businesses in the region.

Jordan Valley Innovation Center

The Jordan Valley Innovation Center (JVIC) operates under a mission of product development for corporate partners and providing interdisciplinary educational experience for students. JVIC is an industry-led, university supported research and development facility designed to accelerate commercialization of new technologies.

Missouri Innovation Center

Missouri Innovation Center supports the creation of new, high-growth ventures, particularly those with a technology component. This is accomplished by leveraging research and innovation by and with the University of Missouri for the benefit of the region and the State.

Missouri Rural Enterprise and Innovation Center

The Missouri Rural Enterprise and Innovation Center facilitates innovation-based economic growth in Northeast Missouri. MREIC provides support to entrepreneurs through one-on-one assistance and links to important resources.

Missouri S&T Office of Technology Transfer and Economic Development (TTED)

The Missouri S&T Office of Technology Transfer and Economic Development (TTED) provides support to S&T faculty, students and researchers to provide IP protection, identify licensees and commercialize university inventions, assisting them to convert their innovative ideas into products, technologies, and services that can benefit society.

Mountain Plains Minority Supplier Development Council

Mountain Plains Minority Supplier Development Council promotes the growth and development of minority businesses through B-to-B opportunities and government contracts.

Newman Business and Technology Innovation Center

The Joseph Newman Innovation Center helps start business in technology other fields and supports existing business. NIC has modern office, light manufacturing and wet lab spaces available.

Northeast Kansas City Chamber of Commerce

NECC strives to be a financially sound, well-managed business association that enhances the quality of life and economic competitiveness in the Historic, contemporary and multicultural district of KCMO.

Northwest Missouri State University Center of Innovation and Entrepreneurism

Dean L. Hubbard Center for Innovation on the Northwest Missouri State University campus provides innovative start up businesses identify resources and support networks.

NSF/S&T I-Corps Site Program

The I-Corps Site experience is a crash course for researchers, students (all levels), alumni and non-academics to encourage technical entrepreneurship by testing research, projects and ideas for their commercial potential.

Ozark Foothills Development Association

The Ozark Foothills Development Association owns and operates a business incubator for new and expanding businesses - low cost rental space from 2300-5000sqft.

Ozarks Small Business Incubator

The Ozarks Small Business Incubator aims to help talented local entrepreneurs gain business skills, build relationships, get funded and grow successful businesses, creating a community of support for small business owners in the Ozarks.

Small Business & Technology Development Center - Missouri University of Science and Technology

The Small Business & Technology Development Center at Missouri S&T offers one-on-one business counseling and group training in the areas of business management, business plan, start-up, marketing, finance and technology commercialization.

Small Business & Technology Development Center - Northwest Missouri State University - St. Joseph Center

The SBTDC offers confidential, one-on-one consulting, coaching and training to existing & emerging businesses as part of their agreement with the U.S. Small Business Administration.

St. Louis Development Corp.

The St. Louis Development Corp. offers programs and services to the small business owner.

St. Louis Economic Development Partnership

The St. Louis Economic Development Partnership seeks to facilitate the development of long-term, diversified business and employment opportunities in St. Louis City and County and the St. Louis region.

STLVentureWorks - Lemay

STLVentureWorks - South County is a 21,000-square-foot business incubator featuring office, warehouse, and production space, and is the only St. Louis facility to offer retail space for start-up and early stage small- to mid-sized businesses.

STLVentureWorks - Wellston

STLVentureWorks - Wellston is a business incubator and a thriving entrepreneurial community that features 20,000-square-feet of office and warehouse space in an area of Wellston that provides easy access to public transportation.

Technology Development Center at Innovation Park

The Technology Development Center at MS&T provides office suites and shared office space for technology oriented tenants. The incubator also offers business building support.


A collaborative effort between several economic development agencies based in St. Louis, Missouri, T-REX is a nonprofit technology incubator, co-working space and innovation conference center, designed to attract talent, create jobs and build density in downtown St. Louis.

UMKC Entrepreneurship Scholars Program (E-Scholars)

UMKC’s entrepreneurship programs accelerate early startups from ideas to sustainable launch in a safe environment of learning, experimenting and mentoring.

University of Missouri-St. Louis - UMSL Accelerate

UMSL Accelerate is the innovation and entrepreneurial resource for students, faculty and the community. Our vision is to serve as a catalyst for developing our students, faculty and community to inspire entrepreneurship and innovation. Our mission is to foster a community of thought leaders by providing a vibrant ecosystem to Educate (curriculum), Innovate (co-curriculum), and Collaborate (community programming).

University of Missouri-St. Louis-Colllege of Education-ED Collabitat

Education Entrepreneur in Residence

WomanSpace Rolla

The mission of WomanSpace Rolla is to provide a safe space for girls and women in the community to meet, learn, and grow, with a focus on arts, education and business.